Restructuring the vocal fold lamina propria with endoscopic microdissection
نویسندگان
چکیده
منابع مشابه
Sulfated glycosaminoglycans in human vocal fold lamina propria.
INTRODUCTION The distribution, concentration and function of glycosaminoglycans in the various vocal fold tissues are still unclear. OBJECTIVE To evaluate the distribution and concentration of sulfated glycosaminoglycans in different layers of the human vocal fold according to gender and age. METHODS We used 11 vocal folds obtained from cadavers (7 men and 4 women) with no laryngeal lesion,...
متن کاملLamina propria replacement therapy with cultured autologous fibroblasts for vocal fold scars.
OBJECTIVES To develop a canine model of vocal fold scar and to evaluate its treatment with lamina propria replacement therapy using autologous cultured fibroblasts. MATERIALS AND METHODS Full thickness of the lamina propria layer in canine vocal folds was injured with a laser. Fibroblasts were cultured and expanded in the laboratory from a buccal mucosal biopsy. The scarred vocal folds were t...
متن کاملDevelopment and maturation of the pediatric human vocal fold lamina propria.
OBJECTIVE To identify characteristic patterns of maturation of the human vocal fold lamina propria as it develops into a mature structure. METHODS Histologic evaluation of sectioned true vocal folds from 34 archived larynges ages 0 to 18 years using hematoxylin-eosin, trichrome, Alcian blue pH 2.5, Weigert reticular, and Miller's elastin stain. LOCATION Pathology department at a tertiary ca...
متن کاملA two-layer composite model of the vocal fold lamina propria for fundamental frequency regulation.
The mechanical properties of the vocal fold lamina propria, including the vocal fold cover and the vocal ligament, play an important role in regulating the fundamental frequency of human phonation. This study examines the equilibrium hyperelastic tensile deformation behavior of cover and ligament specimens isolated from excised human larynges. Ogden's hyperelastic model is used to characterize ...
متن کاملEstablishing principles of macromolecular crowding for in vitro fibrosis research of the vocal fold lamina propria.
OBJECTIVES/HYPOTHESIS Vocal fold fibrosis represents a major disease burden. Screening of antifibrotic compounds could be facilitated by an in vitro fibrogenesis system. Limitations of existing models might be overcome by implication of the excluded volume effect. STUDY DESIGN In-vitro study. METHODS Vocal fold fibroblasts obtained from rats' lamina propria were cultured in four different s...
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ژورنال
عنوان ژورنال: The Laryngoscope
سال: 2013
ISSN: 0023-852X
DOI: 10.1002/lary.24146